If the Captain ignores irregularities noted by the First Officer, what should the First Officer do?

The First Officer should continue to report irregularities until they are resolved because maintaining safety and effective communication is critical in flight operations. The First Officer holds a vital role in the cockpit, and their responsibility includes monitoring flight systems, procedural adherence, and overall safety. If they observe any irregularities, it is imperative to bring them to the Captain's attention consistently.

By continuing to report such issues, the First Officer ensures that any potential safety concerns are fully acknowledged and addressed. This practice promotes a culture of safety and teamwork in aviation, where every crew member's input is valued, and necessary actions are taken to mitigate risks. Ignoring or stopping report procedures can lead to an oversight that could compromise safety. Hence, persistence in communication is a key component in aviating effectively and ensuring that all crew members are in alignment on operational issues.